The four seasons in acute coronary syndrome

Abstract Funding Acknowledgements Type of funding sources: None. Introduction Acute coronary syndrome (ACS) is one the most common health problems in world, and leading cause death. The goals this study are to determine ACS incidence seasonal distribution ocurrence (Spring/Summer/Autumn/Winter) as well clinical outcomes per season. Methods Retrospective observational analysis consecutive patients hospitalized for ST-elevation myocardial infarction (STEMI) Critical Coronary Care Unit (CCCU) a tertiary center with Mediterranean climate from July 2011 September 2022. We analyzed influence seasons on characteristics ACS. Results enrolled total 1668 patients: 431 Winter, 382 Spring, 405 Summer 450 Autumn, baseline summarized Table 1. There were no differences among 4 seasons, except higher prevalence obesity Autumn. was statistically significant difference STEMI although numerically highest recorded occurrence not different according age or sex. complications similar ventricular arrythmias (VT, VF), invasive mechanical ventilation support, need inotrope/vasopressor support development de-novo atrial fibrillation. In-hospital mortality less frequent but did reach statistical significance. Conclusions In cohort, profile found seasons.